Virtual Screening Based on Protein-Ligand Interactions
نویسندگان
چکیده
منابع مشابه
3D Ligand-Based Virtual Screening with Support Vector Machines
Computational models play an important role in early-stage drug discovery, in particular for lead identification and optimization. Starting from a list of molecules with experimentally determined binding affinity to a particular therapeutic target, as typically obtained by high-throughput screening (HTS), the goal of lead optimization is to find additional molecules with good binding affinity. ...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2007
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.127.101